Congratulations to Mayan Rivlin-Gilboa on receiving the Best Hot-topic Presentation Award at the New Trends in DNA-based Data Storage conference in Prague!
Mayan is a graduate student in the field of DNA-based data storage, working under the supervision of Prof. Zohar Yakhini.
The research, Sequence Determinants of CRISPR Off-Target Reaction, was conducted as an effort tangential to the DiDAX project and represents a successful collaboration led by Mark Somoza and Arya Das with data analysis performed by Mayan Rivlin-Gilboa, Guy Assa and Zohar Yakhini.
The study focuses on large-scale mapping of off-target activity in the CRISPR-Cas12a genome editing system and utilizes advanced microarray technology developed in Prof. Somoza’s lab at the Leibniz Institute in Munich. Over 57,000 unique DNA sequences were analyzed to understand how the positions of sequence variants affects CRISPR cleavage efficiency.
The findings contribute to advancing CRISPR precision and to the development of novel DNA-based information applications.
DiDAX is actively working on developing information applications of CRISPR technology.
