The project focuses on developing a simplified synthesis and functionalization strategy for DNA-containing silica nanoparticles to enhance their compatibility with various media and suitability for automation. This includes establishing analytical methods to assess critical performance parameters such as particle homogeneity, agglomeration, dispersion stability, and interactions with different media. The project aims to demonstrate the manufacturability of high-value materials using DNA-based information carriers in at least two high-performance polymers and one medical material, along with testing various methods of incorporating these information carriers into products.
Key tasks include identifying suitable materials and embedding approaches. This involves transitioning from multi-step synthesis processes to a one-pot synthesis using the ammonia-catalyzed Stöber reaction, aimed at combining nanoparticle production and DNA encapsulation in a single step. The optimized nanoparticles will undergo thorough characterization and testing for medium compatibility and manufacturability.
The project will also focus on larger test runs to incorporate digital information into custom-manufactured high-value parts, such as those used in automotive, aerospace, and wind turbine components. The stored data will include essential product information, with rapid aging tests conducted to ensure data recoverability throughout the product’s lifetime.